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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CSK
All Species:
26.22
Human Site:
T445
Identified Species:
48.08
UniProt:
P41240
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P41240
NP_001120662.1
450
50704
T445
E
Q
L
E
H
I
K
T
H
E
L
H
L
_
_
Chimpanzee
Pan troglodytes
XP_001138005
450
50665
T445
E
Q
L
E
H
I
K
T
H
E
L
H
L
_
_
Rhesus Macaque
Macaca mulatta
XP_001101430
450
50702
T445
E
Q
L
E
H
I
K
T
H
E
L
H
L
_
_
Dog
Lupus familis
XP_853247
465
51967
T460
E
Q
L
E
H
I
K
T
H
E
L
H
L
_
_
Cat
Felis silvestris
Mouse
Mus musculus
P41241
450
50595
T445
E
Q
L
E
H
I
K
T
H
E
L
H
L
_
_
Rat
Rattus norvegicus
P32577
450
50728
T445
E
Q
L
E
H
I
R
T
H
E
L
H
L
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P41239
450
50733
E445
E
Q
L
V
H
I
K
E
K
E
L
Y
L
_
_
Frog
Xenopus laevis
NP_001079062
450
50789
A445
E
Q
L
E
H
I
K
A
K
E
L
Y
H
_
_
Zebra Danio
Brachydanio rerio
NP_001071067
450
50999
T445
E
K
L
Q
D
I
I
T
N
E
L
Y
R
_
_
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_731611
1052
113728
Honey Bee
Apis mellifera
XP_393399
493
55500
A486
L
V
L
G
Q
L
K
A
E
Y
T
K
G
V
N
Nematode Worm
Caenorhab. elegans
NP_001021778
539
60138
Sea Urchin
Strong. purpuratus
XP_795344
763
85563
N758
K
H
V
R
S
Q
L
N
L
F
M
S
R
_
_
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
99.7
95.4
N.A.
98.4
98.4
N.A.
N.A.
93.3
83.7
85.7
N.A.
26.6
48.2
43.4
36.8
Protein Similarity:
100
98.4
100
96.1
N.A.
99.3
99.7
N.A.
N.A.
95.3
90.4
93.1
N.A.
32.7
62.8
57.3
45.7
P-Site Identity:
100
100
100
100
N.A.
100
92.3
N.A.
N.A.
69.2
69.2
46.1
N.A.
0
13.3
0
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
76.9
76.9
76.9
N.A.
0
20
0
23
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
16
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
70
0
0
54
0
0
0
8
8
70
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
0
% G
% His:
0
8
0
0
62
0
0
0
47
0
0
47
8
0
0
% H
% Ile:
0
0
0
0
0
70
8
0
0
0
0
0
0
0
0
% I
% Lys:
8
8
0
0
0
0
62
0
16
0
0
8
0
0
0
% K
% Leu:
8
0
77
0
0
8
8
0
8
0
70
0
54
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
62
0
8
8
8
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
8
0
0
8
0
0
0
0
0
16
0
0
% R
% Ser:
0
0
0
0
8
0
0
0
0
0
0
8
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
54
0
0
8
0
0
0
0
% T
% Val:
0
8
8
8
0
0
0
0
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
24
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
77
77
% _